Retraction Note to: Granisetron and dexamethasone provide more improved prevention of postoperative emesis than granisetron alone in children

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Effective dose of granisetron for preventing postoperative emesis in children.

PURPOSE This study was to identify the minimum effective dose of granisetron, a selective 5-hydroxytryptamine type 3 receptor antagonist, to prevent postoperative vomiting in children who have undergone strabismus repair, tonsillectomy or tonsillectomy with adenoidectomy. METHODS In a randomized, double-blind fashion, 80 healthy children aged 4-10 yr were assigned to receive either placebo (s...

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Prevention of postoperative nausea and vomiting in patients undergoing laparoscopic bariatric surgery--granisetron alone vs granisetron combined with dexamethasone/droperidol.

BACKGROUND AND OBJECTIVES Laparoscopic bariatric surgeries are associated with an appreciably high rate of postoperative nausea and vomiting. This study was designed to compare the effectiveness of granisetron either alone or in combination with droperidol or dexamethasone, for the prevention of post operative nausea and vomiting (PONV) in patients undergoing laparoscopic bariatric surgeries. ...

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Granisetron versus Granisetron-Dexamethasone for Prevention of Postoperative Nausea and Vomiting in Pediatric Strabismus Surgery: A Randomized Double-Blind Trial

Aim. Efficacy of granisetron and combination of granisetron and dexamethasone was evaluated for prevention of postoperative nausea and vomiting (PONV) in children undergoing elective strabismus surgery. Methods. A total of 136 children (1-15 years) were included. Children received either granisetron (40 mcg/kg) [group G] or combination of granisetron (40 mcg/kg) and dexamethasone (150 mcg/kg) [...

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Granisetron-dexamethasone combination reduces postoperative nausea and vomiting.

The prophylactic antiemetic efficacy of combined granisetron and dexamethasone was evaluated in a randomized double-blind manner in 88 patients undergoing general anaesthesia for major gynaecological surgery. Immediately after recovery from anaesthesia, patients received a single dose of either placebo (saline, n = 22), granisetron (20 micrograms.kg-1, n = 22), dexamethasone (8 mg, n = 22) or c...

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a randomized comparison of granisetron plus dexamethason with granisetron alone for the control of acute chemotherapy-induced emesis and nausea

introduction: chemotherapeutic drugs used to treat cancer may cause nausea and emesis by inducing the release of 5-hydroxytryptamine (5-ht) in the small intestine. blockage of 5-ht 3 receptors in the small intestine by 5-ht 3 receptor antagonists might prevent the nausea and vomiting associated with chemotherapy for cancer. the aim of this study was to compare the efficacy and tolerability of t...

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ژورنال

عنوان ژورنال: Canadian Journal of Anesthesia/Journal canadien d'anesthésie

سال: 2012

ISSN: 0832-610X,1496-8975

DOI: 10.1007/s12630-012-9829-y